Abstract 6586: Updates to UALCAN, a comprehensive cancer proteogenomic data analysis platform for discovery research (2024)

FAQs

What is the full form of Ualcan? ›

The University of ALabama at Birmingham CANcer data analysis Portal. UALCAN is a comprehensive, user-friendly, and interactive web resource for analyzing cancer OMICS data.

Over the next dozen years, TCGA generated over 2.5 petabytes of genomic, epigenomic, transcriptomic, and proteomic data. The data, which has already led to improvements in our ability to diagnose, treat, and prevent cancer, will remain publicly available for anyone in the research community to use.

The NCDB is a clinical oncology database sourced from hospital registry data collected in more than 1,500 Commission on Cancer-accredited facilities. These data are used to analyze and track patients with malignant neoplastic diseases, their treatments, and outcomes.

What sort of role do you think TCGA information will play in cancer diagnosis and cancer treatment in the future? The common genetic changes associated with each cancer type and subtype are expected to lead to more effective strategies for cancer detection and custom - designed treatment.

Here, we present ONCOMINE, a cancer microarray database and web-based data-mining platform aimed at facilitating discovery from genome-wide expression analyses.

MDS = myelodysplastic syndrome; MDS-EB1, MDS-EB2 = MDS with excess blasts, subtype 1 or 2.

The NCDB, begun in 1989, now contains approximately 40 million records from hospital cancer registries across the United States.

MethMarkerDB is the first cancer DNA methylation biomarker database constructed on WGBS data. This unique resource offers precise genomic location information for biomarkers, encompassing both biomarker genes and DMRs.

Genomic data includes information like the sequence of molecules in an organism's genes. It also includes the function of each gene, the regulatory elements that control gene expression, and the interactions between different genes and proteins.

How is cancer data used? ›

These data are used to understand cancer rates and trends, support cancer research, measure progress in cancer control and prevention efforts, focus action on eliminating disparities, and improve cancer outcomes for all.

Harvard University in Cambridge, Massachusetts, has the world's leading Share of cancer research, and more than one-fifth of its total Nature Index output is in this area.

By analysing patient genomes base-by-base, WGS allows the detection of pathogenic mutations in all regions of the genome – including protein-coding genes and non-coding DNA. When combined with transcriptome analysis, WGS can also give researchers a comprehensive view of cancer as it progresses in response to therapy.

Bioinformatics also helps in identifying common biomarkers and differentially expressed genes in different cancer types which further improves the process of cancer diagnosis.

Clinical cancer researchers conduct clinical trials, study a particular patient or group of patients, including their behaviors, or use materials from humans, such as blood or tissue samples, to learn about disease, how the healthy body works, or how it responds to treatment.

The U.S. Special Operations Command (USSOCOM) oversees the special operations capabilities of the various military branches, coordinates their training, strategy, interoperability and operations.

Health Professions Scholarship Program (HPSP)

Universal Plug and Play (UPnP) is a standard that lets network devices automatically find, communicate with and control each other. It is used by routers, computers, printers, game consoles and IoT devices. It uses industry standard protocols such as IP, HTTP and Extensible Markup Language.

The Royal College of Obstetricians and Gynaecologists (RCOG) is the professional body that oversees the medical education, training and examination of obstetricians and gynaecologists in the UK.